(EN) A Phase III, Randomised, Open-label, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Pembrolizumab Monotherapy for the First-line Treatment of Participants With Locally-advanced or Metastatic Non-squamous NSCLC With High PD-L1 Expression (TC ? 50%) and Without Actionable Genomic Alterations
TROPION-Lung10
NCT06357533
 Actif en recrutement
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CIUSSS DU NORD-DE-L'ILE-DE-MONTREAL
 HOPITAL DU SACRE-COEUR-DE-MONTREAL
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Caroline Chagnon
514-338-2222 poste 2816
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(EN) A Phase III, Two-Arm, Parallel, Randomized, Multi-Center, Open-Label, Global Study to Determine the Efficacy of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for First-Line Treatment of Patients With Metastatic Non-Small Cell Lung Cancer (mNSCLC).
eVOLVE-Lung02
NCT05984277
Actif en recrutement
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CIUSSS DU SAGUENAY – LAC-SAINT-JEAN
HOPITAL DE CHICOUTIMI
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Sabrina Côté
418-541-1000 poste 3065
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(EN) A Randomised, Open-label, Phase 3 Trial Comparing the Efficacy and Safety of OSE2101 Versus Docetaxel in HLA-A2 Positive Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) With Secondary Resistance to Immune Checkpoint Inhibitor
ARTEMIA
NCT06472245
Actif en recrutement
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CIUSSS DU SAGUENAY – LAC-SAINT-JEAN
HOPITAL DE CHICOUTIMI
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Alexandra Simard
418-541-1000 poste 3163
Sabrina Côté
418-541-1000 poste 3065
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(EN) A Phase III, Randomised, Open-label, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Pembrolizumab Monotherapy for the First-line Treatment of Participants With Locally-advanced or Metastatic Non-squamous NSCLC With High PD-L1 Expression (TC ? 50%) and Without Actionable Genomic Alterations
TROPION-Lung10
NCT06357533
Actif en recrutement
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CIUSSS DU SAGUENAY – LAC-SAINT-JEAN
HOPITAL DE CHICOUTIMI
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Sabrina Côté
418-541-1000 poste 3065
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(EN) A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin Versus Docetaxel in Subjects With Previously Treated c-Met Overexpressing, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer
M18-868
NCT04928846
Actif en recrutement
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CISSS DE LA MONTEREGIE-CENTRE
HOPITAL CHARLES-LE MOYNE
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Marie-Ève Yelle
450-466-5000 poste 3281
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(EN) A Phase 3 Randomized Open-Label Study of Adjuvant Pembrolizumab With or Without MK-2870 in Participants With Resectable Stage II to IIIB (N2) NSCLC Not Achieving pCR After Receiving Neoadjuvant Pembrolizumab With Platinum-based Doublet Chemotherapy Followed by Surgery
TroFuse-019
NCT06312137
Actif en recrutement
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CISSS DE LA MONTEREGIE-CENTRE
HOPITAL CHARLES-LE MOYNE
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Marilyn Tessier
450-466-5000 poste 7691
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Évaluation des perceptions des patients atteints du cancer du poumon non à petites cellules de stade avancé envers la chimiothérapie versus l'immunothérapie: un projet pilote
ÉPPIC
n.d.
Actif en recrutement
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CISSS DE L'OUTAOUAIS
HOPITAL DE GATINEAU
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Mai Le
819-966-6100 poste 8134
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(EN) A Phase III, Double-blind, Placebo-controlled, Randomised, Multicentre, International Study of Durvalumab Plus Oleclumab and Durvalumab Plus Monalizumab in Patients With Locally Advanced (Stage III), Unresectable Non-small Cell Lung Cancer (NSCLC) Who Have Not Progressed Following Definitive, Platinum-Based Concurrent Chemoradiation Therapy
PACIFIC-9
NCT05221840
Actif en recrutement
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CISSS DU BAS-SAINT-LAURENT
HOPITAL REGIONAL DE RIMOUSKI
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Isabelle Gagnon
418-724-3000 poste 8029
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(EN) A Phase III, Randomised, Open-label, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Pembrolizumab Monotherapy for the First-line Treatment of Participants With Locally-advanced or Metastatic Non-squamous NSCLC With High PD-L1 Expression (TC ? 50%) and Without Actionable Genomic Alterations
TROPION-Lung10
NCT06357533
Actif en recrutement
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CISSS DU BAS-SAINT-LAURENT
HOPITAL REGIONAL DE RIMOUSKI
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Isabelle Gagnon
418-724-3000 poste 8029
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(EN) A Randomised, Open-label, Phase 3 Trial Comparing the Efficacy and Safety of OSE2101 Versus Docetaxel in HLA-A2 Positive Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) With Secondary Resistance to Immune Checkpoint Inhibitor
ARTEMIA
NCT06472245
Actif en recrutement
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CISSS DU BAS-SAINT-LAURENT
HOPITAL REGIONAL DE RIMOUSKI
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Isabelle Gagnon
418-724-3000 poste 8029
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Groupe d'étude en oncologie du Québec