(EN) A Phase II, Open-Label, Multicenter Study Evaluating the Safety and Efficacy of Neoadjuvant Treatment With Inavolisib Combinations in Patients With Untreated, Early-stage, PIK3CA-Mutated Breast Cancer
BO45853
NCT07054190
 Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Ana Lydia Tkalec
514-890-8000 poste 14186
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Essai randomisé de radiothérapie locorégionale hypofractionnée dans le cancer du sein et le lymphœdème
RHEAL
NCT04228991
Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Mom Phat
514-890-8000 poste 11171
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Étude de phase 3, ouverte, randomisée, comparant le gédatolisib associé au fulvestrant et avec ou sans palbociclib aux traitements standard chez des patientes atteintes d'un cancer du sein avancé HR-positif, HER2-négatif précédemment traitées avec un inhibiteur CDK4/6 en association avec traitement par inhibiteur non stéroïdien de l'aromatase
VIKTORIA-1
NCT05501886
Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Ana Lydia Tkalec
514-890-8000 poste 14186
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(EN) A Randomized, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence
EMBER-4
NCT05514054
Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Ana Lydia Tkalec
514-890-8000 poste 14186
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(EN) A Randomized, Double-blind, Phase 3 Study of Tucatinib or Placebo in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy for Metastatic HER2+ Breast Cancer
HER2CLIMB-05
NCT05132582
Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Ana Lydia Tkalec
514-890-8000 poste 14186
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(EN) Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ Defined by a Molecular Expression Assay Combined With Clinico-Pathological Features
ELISA
NCT04797299
Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Silvine Benth
514-890-8000
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(EN) Breast Cancer Plasma Adjuvant Intra-operative Treatment
Breast Cancer PAINT
NCT06222788
Actif en recrutement
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CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL
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Ana Lydia Tkalec
514-890-8000 poste 14186
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(EN) A Phase 3, Randomized, Multi-center, Open-Label Study of DB-1303 Versus Investigator's Choice Chemotherapy in Human Epidermal Growth Factor Receptor 2 (HER2)-Low, Hormone Receptor Positive (HR+) Metastatic Breast Cancer Patients Whose Disease Has Progressed on Endocrine Therapy
DYNASTY-Breast02
NCT06018337
Actif en recrutement
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CIUSSS DE L'ESTRIE – CENTRE HOSP. UNIV. DE SHERBROOKE
 HOPITAL FLEURIMONT
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Michelle Roy
819-346-1110 poste 12848
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(EN) A Phase III, Open-label, Randomised Study of Neoadjuvant Datopotamab Deruxtecan (Dato-DXd) Plus Durvalumab Followed by Adjuvant Durvalumab With or Without Chemotherapy Versus Neoadjuvant Pembrolizumab Plus Chemotherapy Followed by Adjuvant Pembrolizumab With or Without Chemotherapy for the Treatment of Adult Patients With Previously Untreated Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
TROPION-Breast04
NCT06112379
Actif en recrutement
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CISSS DE CHAUDIERE-APPALACHES
HOTEL-DIEU DE LEVIS
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Pierre Bédard
418-835-7121
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(EN) A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant, a Next Generation, Oral Selective Estrogen Receptor Degrader) vs Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients With ER+/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease
CAMBRIA-2
NCT05952557
Actif en recrutement
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CISSS DE CHAUDIERE-APPALACHES
HOTEL-DIEU DE LEVIS
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Pierre Bédard
418-835-7121
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Groupe d'étude en oncologie du Québec