Essai randomisé de radiothérapie locorégionale hypofractionnée dans le cancer du sein et le lymphœdème
RHEAL
NCT04228991
 Actif en recrutement
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CISSS DE CHAUDIERE-APPALACHES
 HOTEL-DIEU DE LEVIS
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Pierre Bédard
418-835-7121
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(EN) A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
TROPION-Breast05
NCT06103864
Actif en recrutement
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CISSS DE LA MONTEREGIE-CENTRE
HOPITAL CHARLES-LE MOYNE
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Christine Giard
450-466-5000 poste 2278
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(EN) A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With Triple-Negative Breast Cancer Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery
MK-2870-012
NCT06393374
Actif en recrutement
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CISSS DE LA MONTEREGIE-CENTRE
HOPITAL CHARLES-LE MOYNE
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Fanny Raquepas Trudel
450-466-5000 poste 3593
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(EN) A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy With Camizestrant Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) in Patients With ER+/HER2- Early Breast Cancer
CAMBRIA-1
NCT05774951
Actif en recrutement
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CISSS DE LA MONTEREGIE-CENTRE
HOPITAL CHARLES-LE MOYNE
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Christine Giard
450-466-5000 poste 2278
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Essai randomisé portant sur la radiothérapie régionale pour le traitement du cancer du sein avec envahissement ganglionnaire à faible risque avec biomarqueur.
MA.39 (TAILOR RT)
NCT03488693
Actif en recrutement
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CISSS DE LA MONTEREGIE-CENTRE
HOPITAL CHARLES-LE MOYNE
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Caroline Hivon
450-466-5000 poste 2164
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Essai randomisé portant sur la radiothérapie régionale pour le traitement du cancer du sein avec envahissement ganglionnaire à faible risque avec biomarqueur
MA.39
NCT03488693
Actif en recrutement
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CISSS DE LAVAL
HOPITAL DE LA CITE-DE-LA-SANTE
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Phase III |
Solange Tremblay
450-668-1010 poste 23603
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(EN) A Phase III, Open-label, Randomised Study of Neoadjuvant Datopotamab Deruxtecan (Dato-DXd) Plus Durvalumab Followed by Adjuvant Durvalumab With or Without Chemotherapy Versus Neoadjuvant Pembrolizumab Plus Chemotherapy Followed by Adjuvant Pembrolizumab With or Without Chemotherapy for the Treatment of Adult Patients With Previously Untreated Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
TROPION-Breast04
NCT06112379
Actif en recrutement
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CISSS DES LAURENTIDES
HOPITAL DE SAINT-JEROME
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Yanick Sardin Laframboise
450-431-1020 poste 23429
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(EN) A Phase III Randomized, Open-Label Study Evaluating Efficacy and Safety of Giredestrant Compared With Fulvestrant, Both Combined With a CDK4/6 Inhibitor, in Patients With Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer With Resistance to Prior Adjuvant Endocrine Therapy
pionERA Breast Cancer
NCT06065748
Actif en recrutement
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CISSS DES LAURENTIDES
HOPITAL DE SAINT-JEROME
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Yanick Sardin Laframboise
450-431-1020 poste 23429
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(EN) A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With Triple-Negative Breast Cancer Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery
MK-2870-012
NCT06393374
Actif en recrutement
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CISSS DU BAS-SAINT-LAURENT
HOPITAL REGIONAL DE RIMOUSKI
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Isabelle Gagnon
418-724-3000 poste 8029
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(EN) A Phase III, Open-label, Randomised Study of Neoadjuvant Datopotamab Deruxtecan (Dato-DXd) Plus Durvalumab Followed by Adjuvant Durvalumab With or Without Chemotherapy Versus Neoadjuvant Pembrolizumab Plus Chemotherapy Followed by Adjuvant Pembrolizumab With or Without Chemotherapy for the Treatment of Adult Patients With Previously Untreated Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
TROPION-Breast04
NCT06112379
Actif en recrutement
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CIUSSS DE L'EST-DE-L'ILE-DE-MONTREAL
PAV. MAISONNEUVE/PAV. MARCEL-LAMOUREUX
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Audrey Lamoureux
514-252-3400 poste 6258
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Groupe d'étude en oncologie du Québec